Our Program

Expert Ketamine & SPRAVATO® Care in Franklin, TN

Individualized Treatment in a Compassionate, Clinical Setting

Tennessee Ketamine and Wellness Center offers a tailored treatment plan specific to your needs and goals. Our services are delivered in a calm, private, and medically supervised environment, with patient comfort and safety as top priorities. Whether you are exploring intravenous (IV) ketamine therapy or SPRAVATO® for treatment-resistant depression, our experienced medical team is committed to guiding you with clarity, dignity, and compassion.

IV Ketamine Therapy for Mental Health and Chronic Pain

We offer intravenous (IV) infusion of ketamine, administered on-site at the center over a series of visits. For a new patient, we typically recommend 4–6 infusions over the course of a 2–3 week period.

Our medical doctors provide ketamine infusions with safety and patient comfort as our top priority. Every patient undergoes a comprehensive consultation by an anesthesiologist, who closely oversees their individual care. Our team has significant experience developing highly effective ketamine infusion protocols while minimizing side effects.

IV ketamine therapy is available for:

Depression

Major depressive disorder and treatment-resistant depression can leave individuals feeling hopeless, emotionally numb, and disconnected from everyday life. Many patients come to us after trying multiple antidepressants or years of therapy with little success. We use IV ketamine and SPRAVATO® to help patients experience meaningful symptom relief—often within days rather than weeks. These treatments work differently from SSRIs, targeting brain chemistry and neural pathways involved in mood regulation and emotional resilience.

Learn More

Post-Traumatic Stress Disorder (PTSD)

PTSD is more than just a reaction to trauma—it can be a long-term, life-disrupting condition that affects sleep, mood, memory, and the ability to function. Flashbacks, emotional numbness, hypervigilance, and persistent anxiety are common symptoms. Ketamine therapy has shown promising results in helping patients reduce trauma-related distress by enhancing neuroplasticity and interrupting maladaptive thought loops. For those who have not responded to traditional PTSD treatments, ketamine may offer a new direction toward healing.

Learn More

Anxiety Disorders

Persistent anxiety can take many forms—generalized worry, panic attacks, social avoidance—but the result is often the same: a reduced quality of life. For individuals whose anxiety hasn’t improved with conventional treatments, IV ketamine may provide relief. By acting on glutamate receptors in the brain, ketamine helps calm overactive circuits involved in fear and worry. Many patients report a sense of clarity and relief after just a few sessions, giving them space to re-engage with daily life and long-term goals.

Learn More

Obsessive-Compulsive Disorder (OCD)

OCD can create a cycle of intrusive thoughts and repetitive behaviors that are difficult to control. Standard treatments like SSRIs and CBT can help, but many patients don’t find complete relief. Ketamine has been shown to disrupt the rigid thought patterns at the root of OCD by resetting neural activity and promoting cognitive flexibility. We work closely with patients to evaluate their history, determine candidacy, and deliver infusions that align with their needs and goals.

Learn More

Alcohol Use Disorder (AUD)

Alcohol dependence is often compounded by emotional pain, depression, or trauma. For patients in recovery or those struggling with chronic relapse, ketamine can be a powerful adjunct to their care plan. Though not a standalone addiction treatment, IV ketamine has been shown to reduce cravings, lift mood, and support neurobiological healing during early recovery. We offer ketamine treatment as part of a comprehensive, medically supervised approach for patients seeking lasting change.

Learn More

Bipolar Disorder

Bipolar disorder causes intense shifts in mood, energy, and focus—ranging from deep depression to episodes of mania or hypomania. For those who haven’t found relief with traditional medications, ketamine offers a promising alternative. By targeting brain pathways involved in mood regulation, ketamine may help reduce depressive symptoms and promote emotional stability. Our team carefully evaluates each patient to determine if this treatment is a safe and effective option.

Learn More

Complex Regional Pain Syndrome (CRPS)

CRPS is one of the most severe and misunderstood pain conditions. Often triggered by injury or surgery, it causes intense, burning pain, skin changes, and hypersensitivity—sometimes spreading beyond the original site of injury. IV ketamine can help by interrupting the feedback loop between the injured area and the brain, calming the nervous system and reducing pain intensity.

Learn More

Neuropathy

Whether caused by diabetes, chemotherapy, surgery, or injury, neuropathic pain often feels like burning, tingling, or stabbing sensations. Standard medications may not touch this kind of pain. Ketamine works by calming overactive nerve activity, helping patients regain comfort, mobility, and sleep quality.

Learn More

Phantom Limb Pain

Even after a limb is gone, the brain can continue to generate intense pain sensations—sometimes for years. Phantom limb pain is not imagined; it’s neurological. Ketamine helps by recalibrating the brain’s sensory map and quieting the misfiring nerves that cause pain in a limb that is no longer there.

Learn More

Postherpetic Neuralgia

This lingering nerve pain after shingles can be severe, unrelenting, and resistant to conventional treatments. IV ketamine may reduce the sensitivity of affected nerves and help the central nervous system break free from the pain cycle.

Learn More

Trigeminal Neuralgia

Often described as one of the most painful conditions known to medicine, trigeminal neuralgia causes sharp, electric-shock-like pain in the face. Ketamine’s ability to modulate central nerve pathways offers potential relief where traditional medications or surgical procedures fall short.

Learn More

Headache and Facial Pain Syndromes

For patients with chronic migraines, cluster headaches, or facial neuralgia, pain can be constant and disabling. Ketamine has shown promise in reducing headache frequency, duration, and severity—especially in patients who haven’t responded to traditional interventions.

Learn More

Treatment is constantly monitored by a nurse to ensure safety, and a physician is always on-site and immediately available. While ketamine is used off-label for these conditions, its effects are supported by clinical research and our own treatment experience.

SPRAVATO® (esketamine) for Treatment-Resistant Depression

SPRAVATO® is an FDA-approved nasal spray medication for adults with treatment-resistant depression. It is administered in our clinic under required medical supervision.

Each session includes a pre-dose evaluation, followed by on-site administration and a two-hour observation period for monitoring and support. Patients must meet clinical criteria for SPRAVATO® and follow safety protocols established by the Risk Evaluation and Mitigation Strategy (REMS) program.

Insurance coverage may be available for SPRAVATO®. Our staff can help guide you through the prior authorization and benefits verification process.

Getting Started

Your Consultation

Click or call (615) 813-5006 to make an appointment for a comprehensive medical evaluation.

Patient Portal & Intake Forms

We will provide you with a link for our Tebra Patient Portal to facilitate the completion of several Patient Intake Forms.

Assessment Forms

We will send you specific assessment forms for depression, PTSD, anxiety, and/or chronic pain that you can complete quickly and easily on a smartphone or similar device.

No Referral Needed

You do not need to have a referral for your consultation, but it does provide us with more complete information about your health.

Clinical Standards That Prioritize Your Safety and Dignity

Our staff provides support and comfort to patients. We fully explain each procedure so patients know what to expect.

All infusions take place in private treatment rooms, not group settings. Treatments are overseen from start to finish by licensed clinical professionals, with continuous vital monitoring throughout each session.

Treatment plans are personalized and adjusted based on your progress. A physician is always present in the clinic and immediately available should the need arise.

Ready to Begin? Schedule Your Consultation Today

Whether you’re considering IV ketamine or SPRAVATO®, the first step is a confidential consultation with our medical team. We’re here to help you understand your options and create a care plan that supports your goals.

Call (615) 813-5006 to get started. Healing begins with knowledge, safety, and support—and we’re honored to walk this path with you.

Schedule A Consultation

We know how busy life can be, so we offer the option of contacting you based on your preferences to discuss Ketamine Infusion Therapy. Please provide your information below and we will contact you in the timeframe that you choose.